Myelophthisic anemia is a type of anemia that is caused due to the replacement of normal bone marrow by nonhematopoietic or abnormal cells. These abnormal cells ( which could be either cancer cells, granulomas or fibrosis) result in disturbed hematopoiesis due to the following reasons: By physically replacing the native marrow cells By disturbing the […]
Diseases
Postpericardiotomy Syndrome – Causes, Symptoms and Treatment
Postpericardiotomy syndrome (PPS) occurs in a subgroup of patients who have undergone cardiothoracic surgery and is characterized by fever, pleuritic pain, pleural effusion, and pericardial effusion. It occurs due to immune-mediated inflammation of the pleura and pericardium. Postpericardiotomy syndrome after is known to occur following myocardial infarction too and it is called Dressler syndrome. Both fall […]
Macrocytic Anemia: Types, Causes, Investigations and Treatment
Macrocytic anemia is a type of anemia in which the red blood cells are larger than their normal volume. The term ‘macrocytic’ is a Greek word meaning ‘large cell’. Macrocytic anemia comes under the morphological classification of anemia; in which anemia is classified according to the size of red blood cells. The size is reflected in the mean corpuscular volume (MCV). […]
Pernicious Anemia: Causes, Investigations and Treatment
Pernicious anemia is a type of megaloblastic anemia that occurs when a person’s body is unable to absorb vitamin B12 from their gastrointestinal tract. This results in vitamin B12 deficiency and produces morphologically abnormal (unusually large and immature) red blood cells known as megaloblasts. It is also known as Biermer’s anemia, Addison’s anemia, or Addison-Biermer […]
Megaloblastic Anemia – Causes, Pathophysiology, Investigations and Treatment
Megaloblastic anemia is a type of anemia which is characterized by morphologically abnormal (unusually large and immature) red blood cells known as megaloblasts. Causes of Megaloblastic Anemia Megaloblastic anemia has several different causes – deficiencies of either cobalamin (vitamin B12) or folate (vitamin B 9) are the two most common causes. These vitamins play an […]
Bone marrow – Structure, Composition and Functions
Bone marrow is soft, spongy, gelatinous tissue that fills the centers of bones known as medullary cavities. Bone marrow is highly vascular meaning that it is enriched with blood vessels and capillaries. Each day bone marrow produces hundreds of billions of new blood cells. Bone marrow takes over from the liver as the major hematopoietic organ […]
Aplastic Anemia – Classification, Treatment and Prognosis
Aplastic anemia is a rare hematological (blood) disorder in which the bone marrow is damaged resulting in failure to produce all the three major types of blood cells. Bone marrow is a sponge-like tissue inside the bones that makes stem cells that develop into red blood cells (RBCs), white blood cells (WBCs), and platelets. Read […]
Five Types of Diabetes, Not Two, Says New Study
There are five types of diabetes in adults which have different physiological and genetic profiles. This has been suggested by a new research by Scandinavian researchers. The study gathered data on 15,000 patients from across five cohorts in Sweden and Finland and identified five clusters of patients with diabetes using six types of measurements. The […]
Dressler Syndrome Presentation and Treatment
Dressler syndrome is a delayed immune-mediated or secondary pericarditis developing weeks to months after a myocardial infarction characterized by pleuritic chest pain, low-grade fever, and pericarditis. It is also called post-myocardial infarction syndrome. Earlier the syndrome was quite common but the incidence has decreased owing to better reperfusion. This syndrome is now considered under the group postpericardiotomy syndrome which is […]
What is a Capillary Blood Sample
A capillary blood sample is collected by pricking the skin. Capillaries are small vessels formed by branching of arterioles. Blood flows from the heart to arteries, which divide into arterioles, and then further divide into capillaries. After the tissue has been perfused, capillaries then unite to become venules and then widen more to become veins, […]