Replacement of lung parenchyma with fibrous tissue is termed as fibrosis of the lung. It usually occurs due to a reparative or a reactive process.
Causes of pulmonary fibrosis are
Infections
- Tuberculosis
- Pyogenic infections like lung abcess or lobar pneumonia
- Fungal infections of the lung
Pneumoconiosis
Results from breathing in coal dust
Hypersensitivity Reactions
- Diffuse fibrosing aleveolitis
- Farmer’s lung
Collagen Diseases
- SLE
- Systemic sclerosis
Tumours
Drugs
Pulmonary fibrosis can be caused by many drugs
- Busulfan
- Bleomycin
- Nitrofurantoin
- Hydralazine
Other Causes
- Aspiration pneumonitis
- Sarcodosis
- Xanthomatosis
- Histiocytosis
- Mitral stenosis









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