Totally Resistant TB Strain Reported From India

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After Iran, it is India’s turn to report  totally resistant strain of tuberculosis.

The report published in Clinical Infectious Diseases journal on Dec 21, 2011 by Dr Udwadia  et al and comes from Hinduja hospital and medical center in Mahim, Mumbai, reported four cases of this strain.

The strain is called Totally Drug Resistant (TDR).

That makes it resistant to every known drug and it is untreatable. [Read more...]

FDA Clears PICO – A Negative Pressure Wound Thearpy System By Smith Nephew

PICO from Smith and Nepew

Over last twenty years, there has been increased use of negative pressure pumps in order to seal wound dressings and remove edema, or fluid buildup and in turn enhance wound healing.

Smith & Nephew’s new device PICO is a single-use negative pressure wound therapy system has been cleared by FDA and offers advantages to clinicians and patients both.

PICO from Smith and Nepew

The website mentions [Read more...]

A Veyr Happy 2012

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Med Care Tips wishes all its readers a very very happy new year. May it bring health and prosperity.

Take care.

Healthy Heart With DASH Diet Recipes Series – Chicken Salad

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Ingredients

  • 3 1/4 cups chicken breast, cooked, cubed, and skinless
  • 1/4 cup celery, chopped
  • 1 Tbsp lemon juice
  • 1/2 tsp onion powder
  • 1/8 tsp salt [Omit to reduce sodium]
  • 3 Tbsp mayonnaise, low-fat

How  To Make? [Read more...]

Diabetic Person Foot With Non Healing Ulcer Over The Medial Aspect Of Ankle

Ankle Ulcer In Diabetic Foot

Following is a clinical photograph of a diabetic person’s ankle with a non healing ulcer. The person had poor diabetes control

Ankle Ulcer In Diabetic Foot

Ulcer Over Ankle Medial Aspect

With control of diabetes and surgical toileting, the wound healed.

Darunavir Approved BY USFDA For Selected HIV Patients

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The United States Food and Drug Administration has approved once-daily dosing for darunavir boosted with ritonavir for use in adult patients with HIV with no resistance to the protease inhibitor.

Source: Medscape Daily News

How To Insert Naso Gastric Tube or Ryle’s Tube?

How To Insert Naso Gastric Tube or Ryle’s Tube?

Nao gastric tubing is used for many purposes which may be to provide the feed in patients who for any reasons could not be fed through the mouth or to aspirate the gastric content as in poisoning  or during neck surgery for better localization of the esophagus.

While the process needs to be individualzed in every patient, I thought it is good have a video explaining the basics in insertion of nasogastric tube.

See my note at the end after you finish your video.

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Note

The position of the Ryle’s tube can also be confirmed by auscultating the stomach by placing the stethoscope over the area below xiphisternum.

A syringe would push air through the outer end of the tube and a loud audible air entry is heard by the stethoscpoe.

Metabolic Syndrome Linked To Loud Snoring & Sleep Difficulties

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A new study published in Sleep has suggested that loud snoring and sleep difficulties may predict development of the metabolic syndrome, a key risk factor for cardiovascular disease.

The study included  812 participants in the community-based Heart Strategies Concentrating on Risk Evaluation study. Two thirds of participants were women, and 36% were African American. [Read more...]

Older Patients With Stroke Perform Better With Intravenous Thrombolytic Therapy: New Study

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A new analysis has shown that patients older than 80 years with acute ischemic stroke perform better when treated with intravenous thrombolytic therapy than when left untreated.

It further stresses that the older patients would derive similar benefits from thrombolytic therapy as younger patients and are not at significantly greater risk for intracranial bleeding. [Read more...]

What is Short Course Chemotherapy For Tuberculosis?

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Short course chemotherapy is the treatment of TB using a combination of new antitubercular drugs in a fixed regime for a set duration. These regimes have shortened the duration of treatment of TB from the 12-18 months of old regimes using streptomycin, isoniazid, thiacetazone or PAS to 6-9 months.

These new regimes with nearly 100 percent cure rates are much more potent than the older regimes and fewer relapses are reported with them. Their potency, shorter duration of treatment and fewer relapse rates make them a very cost effective treatment of choice for TB.

The regimes essentially consist of treating TB in two phases.

Initial intensive phase (for rapid killing)

Several drugs are given in the initial intensive phase to rapidly reduce the bacillary population in the tubercular lesion. This results in the destruction of drug resistant mutants in the bacterial population and prevents their selective proliferation. In addition, the rapid killing also results in very early sputum conversion, which dramatically reduces the risk of transmission of infection.

A tubercular lesion has four different types of bacilli:

Group 1: Rapidly growing, active bacilli (most bacilli in the lesion belong to this group)

Group 2: Those in the acidic environment inside cells and in cavitary walls.

Group 3: Semidormant bacilli which show occasional spurts in growth (mostly responsible for relapses)

Group 4: Few dormant bacilli. (no drug is yet available against this group)

Each of the 4 drugs used in the initial intensive phase acts on different populations in the tubercular lesion. [Read more...]