A recent article published in Chest has reported that use of Non steroidal antiinflammatory drugs may cause an alteration inn presentation and course of pneumonia.
The article is published in journal Chest in February issue and the authors in order are Guillaume Voiriot, Sandra Dury, Antoine Parrot, Charles Mayaud and Muriel Fartoukh
Nonsteroidal antiinflammatory drugs are used very commonly for pain and fever. The authors wanted to investigate the potential influence of Nonsteroidal antiinflammatory drugs (NSAIDs) on the presentation and short-term outcomes of nonimmunocompromised inpatients with community-acquired pneumonia admitted to the intensive care unit.
The study included 90 patients with community acquired pneumonia admitted to the ICU or step-down unit of a university hospital during a 4-year period. All cases were evaluated prospectively except when they were on long term non steroidal antiinflammatory drugs or steroids .
36% were found to have been administered NSAIDs before they were referred to hospital. This group of patients were younger and had fewer comorbidities as compared to the group who were not given any NSAIDs. [Read more...]