Psychlogical and Social Issues In Hemophilia

Hemophilia is a  chronic, often painful, and sometimes life-threatening illness. At the same time it poses a financial burden and curtails many activities of normal living.

Therefore, the person who has hemophilia her family needs strong support psychological as well as social support.

General

The news of the diagnosis that one has hemophilia could be devastating. Patient should be mentally prepared for bad news. The disease should be discussed in simple terms. Patient should be explained  that the disease is not without treatment and with enough precautions it is possible to live a quality life. [Read more...]

Adalimumab Effective for Treatment of Chronic Plaque Psoriasis of the Hands and Feet

Adalimumab is a TNF inhibitor. A new randomized, placebo-Controlled, double-blind trial published in Archives of Dermatology online December 20, 2010 has suggested that adlaimumab is safe and effective for moderate to severe chronic plaque psoriasis involving hands and/or feet.

The study was  conducted by Craig Leonardi and colleagues and was a multicenter outpatient study in the United States and Canada.

All patients with chronic plaque psoriasis on the hands and/or feet with severity of f “moderate” or above were included in the study. [Read more...]

Cautions For Sports Activity In Hemophilia

In hemophilia sportss activities should be encouraged. The sports activities help by increasing muscle strength. Moreover they also add to self esteem.

Type of Sports

The choice of sports should reflect an individual’s preference, ability, physical condition, local customs, and resources. Low impact activities such as swimming and golf should be encouraged.

High contact sports such as football, rugby, boxing, and wrestling are not advisable.

Before engaing in any sports activity, the patient should consult with a doctor. It is important to find out if a sport is  appropriate for the patient or not. Any special precaution needed, protective gear and requirement of the prophylaxis should be discussed in detail.

Obesity Increases Risk Of Metastasis and Death In Breast Cancer

New research suggests that obesity can affect outcomes in breast cancer. This has been suggested by a study published in Journal of Oncology in November, online.

The study was a  large, retrospective analysis in which researchers concluded that  that obesity is an independent prognostic factor for mortality and developing distant metastases after a diagnosis of breast cancer.

Moreover, adjuvant therapy seemed  to be less effective among obese patients with breast cancer.

The authors say that changes in diet and increased physical activity to achieve a healthier body weight are a cancer-prevention strategy that may also improve the prognosis of patients with curatively resected breast and other cancers

J Clin Oncol. Published online November 29, 2010.
doi: 10.1200/JCO/2010/32.1752

In Allergic Rhinitis, Sublingual Immunotherapy Safe & Effective – Cochrane Systematic Review-

Cochrane Database of Systematic Reviews has published recently that sublingual immunotherapy is safe and effective  in allergic rhinitis.

For this study, the reviewers searched following

  • The Cochrane ENT Group Trials Register; CENTRAL (2010, Issue 3)
  • PubMed
  • EMBASE
  • CINAHL
  • Web of Science
  • BIOSIS Previews
  • Cambridge Scientific Abstracts
  • mRCT
  • Published & unpublished randomized, double-blind, placebo-controlled trials of sublingual immunotherapy in adults and children.

Studies were selected by 2 independent authors, who also examined the risk for bias. [Read more...]

Circumcision May Not Stop Homosexual HIV Transmission

While conducting a study on 1800 men for homosexual HIV transmission, the researchers have found that overall, the risk of contracting HIV did not significantly differ between circumcised and uncircumcised men.

The study has been published in the  online in  AIDS in November..

The researchers hinted that circumcision could be protective among men who primarily had insertive sex with other men. [Read more...]

In Elderly Women High Heart Function Could Be A Bad Thing

A new report published in American Heart Journal say that higher-than-normal ejection fraction can increase her risk of death after acute coronary syndromes.

The authors evaluated  5000 women (age >65 yrs) hospitalized for that indication, those with low left ventricular ejection fraction had the worst outcomes.

However,  2.8% of women with a high left ventricular ejection fraction above 65% also died in the hospital, compared to 1.8% of the group with normal ejection fraction.

Potential factors mentioned for higher ejection fraction in these patients are anemia, hypotension, increased sympathetic tone, and low stroke volume.

Am Heart J.  Posted November 2010. Abstract

Concept Of Comprehensive Care In Hemophilia

Optimal management of these patients, especially those with severe forms of the disease, requires more than the treatment and prevention of acute bleeding.

Keys to improvement of health and quality of life include:

  • Prevention of bleeding
  • Long-term management of joint and muscle damage and other sequelae of bleeding
  • Management of complications from treatment including
  • Inhibitor development
  • Eliminating viral infection(s) transmitted through blood products requiring long-term management.

[Read more...]

How To Prevent A Bleed In Hemophilia Patient

Following measures help to control bleeding in hemophilia patient.

Treat Acute Bleeds

Acute bleeds in hemophilia should be treated early. Whenever possible they should be treated within two hours. [Read more...]

What Is Autism Spectrum Disorder

The autism spectrum disorders  is a spectrum of psychological conditions characterized by widespread abnormalities of social interactions and communication, as well as severely restricted interests and highly repetitive behavior.

Incidence is expected to be around 6 per thousand [Read more...]