45% Increase in Diabetes Preevalence in Past 20 Years

diabetes-care

A new study has based on surveillance data has reported that the prevalence of diabetes among US adults grew by 45% over the past 20 years.

The study has been published online May 1 in Diabetes Care.

This study included 22,586 adults sampled in three periods of the National Health and Nutrition Examination Survey  from 3 periods:

  • 1988 – 1994 (7950 participants).
  • 1999 – 2004 (6756 participants).
  • 2005 – 2010 (7880 participants).

Diabetes was defined as having self-reported diagnosed diabetes or having a fasting plasma glucose level ≥126 mg/dL or HbA1c ≥6.5% (48 mmol/mol).

The researchers looked at the prevalence of diabetes as well as body mass index (BMI), waist-to-hip ratio, waist circumference, and other measures in 3 age groups:

  • Younger adults (aged 20 to 34).
  • Middle-aged adults (aged 35 to 64).
  • Older adults (aged 65 and older).

 

The authors found that number of adults with diabetes increased by 75% from 1988–1994 to 2005–2010 and  the prevalence of diabetes increased over the two decades across all age-groups.

Younger adults had the lowest absolute increase in diabetes prevalence of 1.0%, followed by middle-aged adults (2.7%) and older adults (10.0%).

The authors concluded that during the past two decades, the prevalence of diabetes increased across all age-groups, but adults ≥65 years of age experienced the largest increase in absolute change.

Obesity was strongly associated with the increase in diabetes prevalence, especially in adults <65.
The limitation of the study was study were

  • Cross-sectional study
  • Did not distinguish between type 1 and type 2 diabetes
  •  One time measurement to establish undiagnosed diabetes.

Source

  • Diabetes Care. Published online May 1, 2013. Abstract

Patients with Diabetic Nephropathy & Microalbuminuria Show Fastest Reduction in Glomerular Filtration Rate

diabetes-care

A study from Japan has reported the having diabetic retinopathy and/or microalbuminuria predicted a much higher rate of annual decline in glomerular filtration rate.

The study is based on data from the Japan Diabetes Complications Study and was published online April 25 in Diabetes Care.

Diabetic retinopathy is a known risk factor for microalbuminuria, and microalbuminuria is a risk factor for macroalbuminuria, but authors wanted to find if  diabetic retinopathy predicts poor renal function.diabetes-care

For the study, 1475 patients in the Japan Diabetes Complications Study were divided into 4 groups: [Read more...]

New Guidelines :Screening Recommended For All Patients Between 15-65 – US Preventive Services Task Force

HIV test

In a recent study published on April 30 in the Annals of Internal Medicine US preventive Services Task Force has recommended that all the patients between age 15 to 65 years should be screened for HIV as it would substantially decrease the HIV disease burden across the country.

This recommendation would also dramatically reduce transmission of the virus, and markedly curtail infected patients’ progression to AIDS and death.

In 2005, screening of only at risk patients were recommended. [Read more...]

What Are Causes of Vomiting

vomiting

Vomiting is forceful expulsion of content of stomach through mouth and sometimes nostril. Medical term for vomiting is emesis.

Vomiting can occur due to a number of reasons which include following

Digestive Tract

  • Gastritis and Gastroenteritis
  • Pyloric stenosis (Results in a very forceful projectile vomiting)
  • Bowel obstruction
  • Overeating especially in children
  • Peritonitis
  • Food allergies
  • Cholecystitis, pancreatitis, appendicitis, hepatitis
  • Food poisoning

[Read more...]

Stomach Ulcer Video

Stomach Ulcer Video

This is a video of a young patient with chronic abdominal pain. After an evaluation with blood work and an ultrasound of the abdomen, an upper endoscopy was performed that revealed a large gastric ulcer in the antrum/pylorus of the stomach. Several smaller erosions were also noted in the stomach.

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Understanding Heartburn

Understanding Heartburn

What is heartburn is very well explained by this video
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What is Heartburn and What Causes It

heartburn

heartburnHeartburn is  also known as pyrosis  cardialgia, or acid indigestion.

It is  an uncomfortable warm and burning sensation in the chest, usually  behind the sternum  and is more common immediately after eating.

Cause
In spite of the term, the condition has got nothing to do with heart conditions.

Heart burn is linked to acid reflux from the stomach.

When we ingest food, it is taken to the stomach for digestion.

The esophagus is a long tube about 10 inches  in  adults that connects throat to the stomach. When food is swallowed,  a wavelike motion occurs  in the muscles lining the esophagus to propel the food towards the  stomach.

On reaching the end of the esophagus the food passes through  lower esophageal sphincter (LES), a ring of muscle  before it enters  the stomach. LES is like a  one way valve that opens inward to allow entry into the stomach and closes when food has entered the stomach.

Pressure exerted on the valve from the stomach only further seals it.

Sometimes, due to a malfunctioning LES, acid reflux and heartburn occur.

Some LESs don’t form a tight seal when closed, and others will relax randomly when there is still work to be done. When the LES relaxes with food still in the stomach, pressure from the fullness of the stomach or  physical movement  can force the contents back up  into the  esophagus.

The pain of heartburn is the irritation or damage taking place to the esophagus by the refluxed stomach acid.

It is common for people to have heartburn occasionally.

Gastroesphageal reflux disease is most common cause of heartburn.

Following habits are known to increase risk of heartburn

  • Foods like coffee, alcohol, tomatoes, fatty or spicy foods, and chocolate.
  • Smoking
  • Tight clothing
  • Medical conditions like hiatus hernia, peptic ulcer, obesity, neurosis etc.

Signs and symptoms of Heartburn

Signs and symptoms of heartburn include:

  • An uncomfortable sensation of warmth or burning in the chest lasting for few minutes to few hours [ After eating, or during sleep]
  • Worsening of the pain on lying down or bending over
  • Burning sensation in the throat
  • Sensation of food sticking in the middle of the chest or throat

Diagnosis

Most of the the diagnoses are based on clinical history and examination.

Investigations

Prevention

Following measures can reduce the risk of developing heartburn.

  • Loosing weight
  • Quit smoking
  • Smaller meals
  • Take evening meals at least  three hours before going to bed
  • Avoid food triggers – some foods and drinks may trigger heartburn in some patients.
  • Raise head end of your bed slightly

Treatment

Following drugs are commonly used for ailment

  • Antacids  neutralize stomach acid and provide rapid relief.
  • H-2-receptor blockers – they work more slowly than antacids, but provide longer relief.
  • Proton pump inhibitors – these block the production of acid, giving damaged esophageal tissue time to repair itself’.

Periodic Fasting Helps Children With Epilepsy

Periodic Fasting Helps Children With Epilepsy

Children with persistent and drug-resistant seizures treated with the high-fat, low-carbohydrate ketogenic diet may get an added therapeutic benefit from periodic fasting, according to a small Johns Hopkins Children’s Center study.

The results, published online Dec. 3 in the journal Epilepsy Research, suggest the ketogenic diet and fasting can work in tandem to reduce seizures but appear do so through different mechanisms — a finding that challenges the longstanding assumption that the two share a common mechanism.

In the study, six children, ages 2 to 7, and all on the ketogenic diet, were asked to fast on alternate days. [Read more...]

Vitamin C and beta-carotene are Protective Against Alzhiemer’s Dementia

medcare-default

Alzhiemer’s disease is a dreadful condition that takes away the memory  of  the affected person. It affects one in eight older Americans and more than half over the age of 80 years.

Though a medical drug breakthrough is awaited despite spending billions on research, it is now established that oxidative stress plays a vital role in pathogenesis of AD.

This has led to scientists study the effect of antioxidants. [Read more...]

Risk of Celiac Disease Increases in Children With Early Infections

children

According a new study, published in Biomedcentral Pediatrics, infections in children younger than 2 years may be linked to an increased risk for celiac disease.

The study by Anna Myleus and colleagues has been published in the December 2012 issue of Biomedcentral Pediatrics.

The authors also reported a synergistic effect between early infections and daily amount of gluten intake.

Celiac disease is a chronic small intestinal immune-mediated enteropathy which is precipitated by exposure to dietary gluten in genetically predisposed individuals.

The authors reported that Sweden has experienced an “epidemic” of celiac disease in children below two years of age. [Read more...]