University of Montpellier Experts Relate Depression To Cholesterol Level and Gender

Do you know the Institute of Health and Medical Research (INSERM) and School of Montpellier financed experts indicated that regulating ‘good’ and ‘bad’ levels of cholesterol can help prevent mood problems among seniors?

In a newly released issue of the journal Biological Psychiatry (http://www.biologicalpsychiatryjournal.com) written in July 2010, leading researcher Dr. Marie-Laure Ancelin of INSERM (Institut National de la Santé et de la Recherche Médicale http://www.inserm.fr) announced that gender specific regulation of cholesterol levels can help stop depressive disorder in the aging seniors. [Read more...]

The Concept Of Comprehensive Care In Hemophilia

Hemophilia is manifested by bleeding disorder. But it is more than a bleeding disorder and is complex disorder in terms of diagnosis and management.

Therefore the management of these patients requires a lot more than the treatment and prevention of acute bleeding.

Objectives of Care of Hemophilia are [Read more...]

What Is Hemophilia?

Hemophilia is an X-linked congenital bleeding disorder  caused by a deficiency of coagulation factor VIII (hemophilia A) or factor IX (hemophilia B).  Hemophilia A is more common (85% of the total) than hemophilia B.
When To Suspect Hemophilia?

  • Easy bruising in early childhood
  • Spontaneous bleeding particularly into the joints and soft tissue
  • Excessive bleeding following trauma or surgery.

[Read more...]

What Are Symptoms of Addison Disease?

Addison’s disease is also called as chronic adrenal insufficiency, hypocortisolism or hypocorticism. It is a rare disorder where the adrenal glands are not able to produce glucocorticoids and less often mineralocorticoids in sufficient quantity. The condition was first described by Dr Thomas Addison, the British physician who first described the condition.

Causes of Addison disease

Adrenal dysgenesis

This means adrenal glands which produce glucocorticoid are absent. [Read more...]

Routine Investigation of Polymerase Chain Reaction & ELISA in Tuberculosis

Polymerase chain reaction

polymerase_chain_reactionWith the help of PCR, millions of identical copies of any specific DNA or RNA sequence can be made. This sequence may be a gene, or a part of gene, or simply a stretch of nucleotides.

This is done by using highly specific oligonucleotide primers to amplify the target nucleic acid by repeated rounds of denaturation, primer annealing and amplification. The target DNA is amplified a billion fold within 2-4 hours, and becomes quantitatively enough to be detected by a variety of detecting system. [Read more...]

Skin Reactions During Treatment of Tuberculosis

In such cases withdraw and do not restart ATT till the rash has subsided completely. Once the rash has subsided, the offending drug has to be first identified.

If thaicetazone was used, it should not be used again. Other drugs should be reintroduced one by one  first in small doses.

The order of reintroduction of the drugs depends on the relative likelihood of the drugs to cause a skin reaction. The least likely drug is introduced first. The chart suggests a practical approach to identify the offending drug. [Read more...]

What Is Mercer Disease and What Causes It?

Mercer Disease is another name for methicillin resistant staphylococcus aureus [MRSA] infection.MRSA is resistant to the antibiotics typically used to treat staph infections. Because of the resistance to many antibiotics, Mercer Disease can be fatal.

Staphylococcus

This bacteria is commonly found in a person’s nose or on the skin. Unless the bacteria enters the body through a wound or cut, it can be harmless. Most MRSA infections occur in health care environments, such as hospitals, dialysis centers and nursing homes. [Read more...]

What Is Inflammatory Heart Disease?

The heart disease that is consequence of an inflammation is called inflammatory heart disease. This may be due to an  infection that develops from a bacteria or virus or inflammation due to some internal milieu. Depending upon the layer of heart involved it could be  myocarditis, pericarditis or endocarditis.

Myocarditis

Myocarditis describes any inflammation that occurs within the heart muscle. It is induced by viral infections, diseases like sarcoidosis, and immune disorders. [Read more...]

What Are Different Types Of Heart Diseases

Heart disease is also called cardiopathy. Both of these are kind of umbrella term for a variety of different diseases affecting the heart. Heart disease can be of following types

Coronary Heart Disease
It implies the  failure of the circulation to cardiac muscle and surrounding tissue. Coronary heart disease is most commonly equated with Coronary artery disease although coronary heart disease can be due to other causes.

Coronary artery disease is a disease of the artery caused by the accumulation of atheromatous plaques within the walls of the arteries that supply the myocardium. [Read more...]

What Is End Stage Heart Disease

American Heart Association classifies the chronic heart failure as follows

A. High risk for developing heart failure

  • Hypertension, diabetes mellitus, CAD, family history of cardiomyopathy

B Symptomatic heart failure

  • Previous MI, LV dysfunction, valvular heart disease

C Symptomatic heart failure

  • Structural heart disease, dyspnea and fatigue, impaired exercise tolerance

D Refractory end-stage heart failure

  • Marked symptoms at rest despite maximal medical therapy

Thus end stage heart disease is a condition in which the heart can no longer pump enough blood to fulfill the body’s metabolic requirements. [Read more...]

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