α4-integrin

January 11, 2012 By Arun Pal Singh Leave a Comment

The integrins generally consist of alpha-beta heterodimeric transmembrane glycoproteins in which the alpha subunit is noncovalently associated with the beta subunit.

Integrin, alpha 4 belongs to the integrin alpha chain family of proteins. Unlike other integrin alpha chains, alpha 4 neither contains an I-domain, nor undergoes disulfide-linked cleavage.

Alpha 4 chain associates with either beta 1 chain or beta 7 chain.

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