Health and Medical Care Tips
Though age old stigma with tuberculosis has educed but people still have misconceptions about the disease, its contagiousness and the way it can affect others.
Clear communication is the keystone of patient diagnosis and it begins with telling the correct diagnosis and counseling the patient and family.
It is preferable to counsel the family together to begin with, to educate them and to dispel myths and to gain their support towards regular compliance by the patient. [Read more...]
Natural killer cells are sonamed because they are potent cytotoxic cells whose targets are not restricted i.e., they are not antigen-specific. They make up 5-10 percent of the lymphocyte population.
They are activated by IL-15.
They have the appearance on light microscopy of large lymphocytes with numerous cytoplasmic granules and are sometimes called large granular lymphocytes. The granules contain substances that facilitate target cell lysis including perforin (a pore-forming protein) and granzymes. They classically express the CD16 and CD56 cell-surface markers. [Read more...]
The Mantoux test is very widely used test for tuberculosis. Its interpretation however complex. It is also called tuberculin test.
Tuberculin is a glycerol extract of the tubercle bacillus. Purified protein derivative (PPD) tuberculin is a precipitate of non-species-specific molecules obtained from filtrates of sterilized, concentrated cultures.
The test is named after Charles Mantoux, a French physician who developed on the work of Koch.
Procedure
A standard dose of 5 Tuberculin units (0.1 mL) is injected intradermally and read 48 to 72 hours later. A person who has been exposed to the bacteria is expected to mount an immune response in the skin containing the bacterial proteins. [Read more...]
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