A Short Note On Lipoma

Lipoma in A Forearm<br>Image Credit Wiki media Commons

Lipoma in A Forearm

A lipoma is the commonest and most benign of all tumours. It is composed of fat cells of adult type. It can occur anywhere in the body, that is why it is often called ‘universal tumor’ or ‘ubiquitous tumour’.

But the common sites are the subcutaneous tissue of

  • The trunk
  • Nape of the neck
  • The limbs.

Varieties: Mainly there are three varieties

  • Encapsulated lipoma
  • Diffuse lipoma
  • Multiple lipomas:

Diffuse Lipoma

This is a rare variety and does not possess the typical features of lipoma, hence it is often called ‘pseudolipoma’. It is seen in the subcutaneous and intermuscular tissues of the neck. It is not a typical tumour but an overgrowth of the fat in this region.

It does not possess the capsule which is typical of a lipoma. It gives rise to a disfiguring swelling at the neck. It is often found in persons taking excessive alcohol.

Treatment is excision of the excess of fat if it is required by the patient due to cosmetic reason.

Multiple lipomas:

Such variety is not uncommon. It is often called lipomatosis. The tumours remain small or moderate in size and are sometimes painful as these often contain nerve tissue and are called neurolipomastosis. These are mostly seen in the limbs and in the trunk.

Lipomata of different sizes and shapes may be seen. Macroscopically and microscopically these are not different from solitary lipoma. Dercum’s disease (adivosis dolorosa) is a variety of this condition in which there are tender lipomatous swellings particularly affecting the trunk.

A few lipomas may contain other tissues and names accordingly-

  1. Fibrolipoma – when a lipoma contains an excessive amount of fibrous tissue.
  2. Naevolipoma – when a lipoma contains excessive vascularity with telangiectasis of the overlying skin.
  3. Neurolipoma – when a lipoma contains nerve tissue. It is often painful.

Complication

A lipoma when present for a long time may undergo certain changes. This is particularly true in case of lipoma in the subcutaneous tissue of the thigh, buttock or a retroperitoneal lipoma. Such changes are: (i) Myxomatous degeneration (ii) Saponification (iii) Calcification (iv)malignant or sarcomatous change. Though liposarcoma is not uncommon, yet a lipoma turning into liposarcoma is not so common.

Clinically a lipoma can occur in different anatomical situations.

According to this a lipoma can be classified into-

  1. Subcutanous type: This is the commonest variety. Although any part of the body can be affected, yet it shows particular tendency to occur in the back, nape of the neck and on the shoulders. Subcutaneous lipoma is usually sessile, but occasionally may become pedunculated. The characteristic features of such lipoma are described below.
  2. Subfascial lipoma: Lipoma may occur under the palmar or plantar fascia and is often mistaken as tuberculous tenosynovitis. Such lipomas may also occur in the areolar layer under the epicranial aponeurosis in the scalp. Subfascial lipoma can be confused with a dermoid cyst, particularly so, as such lipoma may also erode the underlying bone as the dermoid cyst. Treatment is urgent excision of the tumour.
  3. Intermuscular lipoma: Such lipoma occurs between the adjacent muscles and becomes firmer on feel when the adjacent muscles contract. Mechanical interference with the action of the muscles is often complained of. Fibrosarcoma is also common in such situation and is difficult to differentiate from this condition clinically. Intermuscular lipoma is mostly seen in the thigh or around the shoulder. Treatment is early excision as it is difficult to differentiate from fibrosarcoma.
  4. Subserous lipoma: This is rare and is sometimes found beneath the pleura or peritoneum. When it is beneath the pleura it presents as a benign thoracic tumour. Retroperitoneal lipoma is also rare and is often misdiagnosed as hydronephrosis, pancreatic cyst or teratomatous cyst. A retroperitoneal lipoma may attain a big size. Very occasionally one may find a lipomatous mass rather than a lipoma at the fundus of the sac of a femoral hernia. This is a condensation of extraperitoneal fat rather than a typical lipoma.
  5. Submucous lipoma – is also rare. It may occur in the respiratory or elementary tract. It is also seen in the tongue. In the respiratory tract it may cause respiratory obstruction. In the intestine it may lead to intussusception.
  6. Intra-articular – inside the joint. It is extremely rare.
  7. Subsynovial lipoma – such lipoma occurs deep to the synovial membrane in the fatty pad. It is seen in the knee joint. In this case it is often compared with Baker s cyst or a bursitis.
  8. Parosteal lipoma - occurs under the periosteum of a bone
  9. Extradural lipoma: This is a type of spinal tumour. Intracranial lipoma does not occur as there is no fat in the extradural tissue within the skull.
  10. Intraglandular lipoma: There are 3 glands in which a lipoma may be seen (i) the breast (ii) the pancreas and (iii) under the renal capsule.

What Is Hypertension – Causes, Signs, Symptoms and Treatment

Hypertension is the silent killer of mankind. Most sufferers (85 percent) are asymptomatic and hence early diagnosis is a problem. The dividing line between normal and abnormal BP is arbitary because BP is dependent upon many factors like age, race, sex, etc.

Definitions

The definition of hypertension is not universal because normal BP varies. However, diastolic pressure below 85 mmHg is considered normal, between 86 and 89 mmHg high normal, between 90 and 104 mmHg mild hypertension, between 105 and 114 mmHg moderate hypertension and above 115 mmHg severe hypertension.

Borderline systolic hypertension: The diastolic BP is normal and systolic BP is between 140 and 159 mmHg.

Isolated systolic hypertension: The systolic BP is 160 mmHg and above and fluctuates from time to time, high in the morning and low at night.

Labile hypertension: The patient is hypertensive at one time and normotensive at another time.

Malignant hypertension: Hypertension is associated with complications like papilledema, retinal exudates, hemorrhage. No absolute BP level can be assigned for this condition. However, these patients usually have BP around 200/140 mmHg.

Accelerated hypertension: Denotes a recent rise in BP with retinal damage but without papilledema.

Causes

1. Essential Hypertension
2. Renal

  • Acute nephritis,
  • Interstitial nephritis and pyelonephritis
  • Polycystic kidneys
  • Renal artery stenosis

3. Vascular: Arteriosclerosis, coaractation of aorta
4. Endocrine: Pheochromocytoma, Cushing’s syndrome, thyrotoxicosis, myxedema.
5. Neurological: Raised intracranial tension, lead encephalopathy, etc.
6. Miscellaneous: Polycythemia, aortic incompetence, toxemia of pregnancy, periarteritis nodosa, gout, etc. [Read more...]

What Can Cause Pallor

Pallor is paleness of skin and mucous membrane either as a result of diminished circulating red blood cells or diminished blood supply.

Causes

  1. Anemia
  2. Shock
  3. Peripheral vascular diseases

Sites where anemia is detected:

  1. Lower palpebral conjunctiva
  2. Tongue
  3. Soft palate
  4. Palm and nails

Checklist for General Examination of A Patient

The general examination of the patient must be done systematically, noting the following:

  1. Built
  2. Body proportions
  3. Nutrition
  4. Decubitus
  5. Clubbing
  6. Cyanosis
  7. Jaundice
  8. Pallor
  9. Lymphadenopathy
  10. Edema
  11. Skin, hair and nails
  12. Vertebral column
  13. Joints
  14. Temperature
  15. Pulse
  16. Blood pressure
  17. Respiration

Dermoid Cyst – Tubulo Dermoid and Teratomatous Dermoid

Tubulo-Dermoid

This is also an epidermal cyst, but such cyst develops from an unobliterated portion of a congenital ectodermal duct or tube.

Pathology:

The cyst is formed by accumulation of secretion of the lining ectodermal cells of the unobliterated portion of an embryonic duct.

Examples

  1. Thyroglossal cyst: develops from the thyroglossal duct. It is the commonest example of tubulo-dermoid cyst.
  2. Post-anal dermoid: develops from remnant of neurenteric canal or post-anal gut. But it is now regarded as a simple form of teratoma.
  3. Ependymal cyst is in the brain- from the sequestration of cells derived from the infolding neuroectoderm.

Treatomatous Dermoid

This is a cystic swelling develops from the totipotent cells with ectodermal predominance. Such cyst also contains mesodermal elements like bone, cartilage etc. Hairs are almost always present in such cyst. So the usual contents are bone, cartilage, tooth, hair and cheesy material.

Common sites are

  1. Ovary-ovarian cyst
  2. Testis- teratoma
  3. Mediastinum- mediastinal cyst
  4. Retroperitoneum- retroperitoneal cyst
  5. Post- anal dermoid

List of Conditions That cause Cramps

  • Electrolyte disturbances
    • Hyponatremia
    • Hypocalcemia
    • Hypomagnesemia
  • Neurological
    • Amyotropic lateral sclerosis
    • Muscular dystrophy
    • Myotonia
    • Peripheral neuritis
  • Metabolic
    • Uremia
    • McArdle’s disease
  • Occupational
    • Miners
    • Writers
    • Typists
    • Tailors
    • Telephone operators
  • Miscellaneous
    • Pregnancy
    • Dehydration
    • Chronic wasting disease
    • Overexertion
  • Idiopathic

List of Causes of Intermittent Claudication

Intermittent claudication is theCramping pain or weakness in the lower extremities during use of limbs, caused by blockage of the circulation.

    • Arterial
      • Atheroma
      • Embolism
      • Buerger’s disease.
    • Systemic
      • Diabetes mellitus
      • Syphilis
      • Anemia
      • McArdle’s disease
      • Overexertion.

    Sebaceous Cyst

    Sebaceous glands are present in the skin. These glands secrete sebum which keeps the skin soft and oily. The duct of the sebaceous gland mainly opens into the hair follicle and rarely may open becomes distended with its own secretion and forms a sebaceous cyst. This is a retention cyst and is most accurately called epidermoid cyst since such cyst is lined by superficial squamous cells.

    Pathology

    Such cyst is lined by squamous epithelium and contains sebum which is yellowish pultaceous material with unpleasant smell. Such material contains sebum, fat and desquamated epithelial cells. Situated in the dermis it raises the epidermis to produce a firm elastic dome-shaped protuberance. At the central point of protuberance it is tethered to te epidermis at a black spot which is keratin-filled punctum.

    Common sites

    A sebaceous cyst can be seen anywhere in the body but most commonly seen in those parts where there are plenty of sebaceous glands. Such sites are (i) The scalp (ii) Face (iii) Neck (iv) Shoulders (v) Chest (vi) Scrotum. The characteristic feature in scrotum is – that the cysts are multiple and when well formed they feel solid. Punctum is often not visible.

    There is no sebaceous gland in the palm or sole, so sebaceous cyst is never seen in these areas.

    Clinical features

    1. It may occur at any age from young to old, but rare in childhood.
    2. It is a typical cystic swelling which is spherical in shape. Its size varies from a few millimeters to about 5 cm in diameter. The surface is smooth and there is a blackish spot or punctum which indicates the blocked opening of the duct.
    3. Such cyst is always fixed to the skin, so the overlying skin cannot be lifted off the swelling (cf. dermoid cyst and lipoma). The consistency is cystic. Due to presence of sebum there may be indentation due to pressure with finger tip. If the cyst is a big one, fluctuation test may be positive, otherwise it is difficult to perform. This cyst is free from underlying structures and it can be moved easily with the skin.
    4. Transillumination test is almost always negative, as the content is thick and does not allow light to pass through it
    5. The swelling is usually not tender. In case it is tender, the cyst is obviously infected.

    Treatment

    Total excision of the cyst is the treatment of choice. If the cyst is infected, preliminary antibiotic treatment should be give and the excision is only possible when the infection has subsided.
    If the cyst is a small one it can be excised under local anaesthesia

    Two kinds of procedure may be adopted-

    1. Dissection method: An elliptical incision is made on the skin including the punctum. The cyst is gradually dissected from the surrounding skin till the entire cyst can be removed intact. It must be remembered that the whole of the cyst wall must be removed, otherwise recurrence is inevitable. Such dissection method is particularly applicable when the cyst was infected previously since this will make the cyst wall well defined and thick.
    2. Incision – avulsion technique: Under local anaesthesia an incision is made through the skin into the cyst. Some contents of the cyst are squeezed out. The cyst wall is then held with a pair of dissecting forceps and the cyst is carefully avulsed out.

    Treatment of Scrotal Sebaceous Cyst

    1. If it is solitary- excision of the cyst should be performed.
    2. If the cysts are multiple affecting a part of the scrotal skin- that part of the scrotal skin including the sebaceous cysts should be excised.
    3. If the cysts are multiple and scattered all over the scrotal skin- the whole of the scrotal skin should be excised and the testes have to be placed in pockets made in the subcutaneous tissue at the medial side of the respective thigh.

    Complications

    Infection:

    The sebaceous cyst is very prone to infection. when it is infected, the overlying skin becomes red. When infection sets in, it may culminate to suppuration. A sebaceous cyst may be repeatedly infected. Once infected, antibiotic treatment should be started.

    If the infection subsides, excision of the cyst should be carried out as mentioned above. If infection does not subside with antibiotic treatment, it should be incised and the pus and semiliquid foetid material are expelled. Now the cyst wall is gradually dissected out or avulsed under antibiotic cover.

    Ulceration:

    This complication arises when an infected cyst ruptures by itself and discharges its contents. The ulcer is covered by granulation tissue. It may look like an epithelioma. When the sebaceous cyst of the scalp ulceraes, excessive granulation tissue forms resembling fungating epithelioma. This is called the Cock’s peculiar tumor.

    It looks angry and sore. The granulationtissue arises from the lining of the cyst, heaps up and bursts through the skin giving the lesion an everted edge. Infection in the cyst wall and surrounding tissues makes the whole area oedematous, red and tender. The regional lymph nodes are often enlarged.

    Sebaceous horn:

    slow discharge of sebum from a wide punctum sometimes hardens. This forms the sebaceous horn.

    Clacification:

    This is a rare complicationthough it is sometimes seen in the sebaceous cyst of the scrotum.

    Malignancy:

    Very rarely malignancy may develop in a sebaceous cyst which if often in the form of basal cell carcinoma.

    Causes of Vertigo

      • Cerebellar
        • Cerebellitis
        • Cerebellar injury
        • Infarction
      • Brain Stem
        • Vertebrobasilar insufficiency.
      • Vestibular
        • Neuronitis
        • Acoustic neuroma
        • Cerebello pontine angle tumou
      • Auditory
        • Acute labyrinthitis
        • Meniere’s disease
        • Toxic effects of alcohol
        • Streptomycijn therapy
        • Salicylates toxicity
        • Eustachian tube blockage
      • Miscellaneous
        • Migraine
        • Aura of epilepsy
        • Anemia
        • hypotension
        • Head injury

      What Can Cause Tinnitus

        • Wax in the ear
        • Polyp of ear
        • Foreign body of the ear
        • Middle ear inflammation
        • Menier’s disease
        • Labyrinthitis
        • Acoustic neuroma
        • Migraine
        • Barotraumas
        • Anemia
        • Aortic regurgitation
        • Salicylate
        • Quinine